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. 2023 Feb 22;15(5):1381. doi: 10.3390/cancers15051381

Table 5.

Recommended areas for future scanxiety research.

Research Topics: Expanding Research to Areas Needing Additional Attention
Suggested Areas Example Research Questions
Investigate care partners’ scanxiety levels and supportive care needs
  • What are the scanxiety characteristics, levels, and support needs among care partners/family members?

  • How do care partners’ scanxiety compare to and influence that of the cancer survivor?

Determine whether people with cancer experience similar anxiety and uncertainty while awaiting different types of tests
  • How does anxiety fluctuate in the time period around cancer-monitoring blood tests and results delivery?

  • What are the components or dimensions of anxiety around these procedures?

  • What are the correlates and effects of anxiety around other tests?

Explore how newer modes of scan results delivery (e.g., via electronic results release; via video or other remote clinical interactions) affect scanxiety
  • Which patients experience decreased anxiety when receiving faster, automated test results (e.g., in patient portals)—and which patients experience elevated anxiety?

  • What support strategies may patients need in order to engage with and benefit from this format of results delivery?

Expand scanxiety research to under-investigated populations, time periods, and scan types
  • What are the scanxiety experiences and coping strategies of those with hematological malignancies?

  • How does anxiety fluctuate between the scan procedure and the scan results? What factors may exacerbate or buffer against increases?

  • How do patients cope with anxiety in the context of investigative scans prompted by new or worsening symptoms?

  • What are the longitudinal patterns of scanxiety that occur over time with repeated scans?

Expand work on the effects of scanxiety and moderators of these effects
  • For whom and how does scanxiety affect one’s likelihood of adhering to follow-up care?

  • How does scanxiety impact physical symptoms, communication in appointments, and other outcomes?

Determine intervention targets and test whether interventions are effective
  • Are brief interventions (e.g., just-in-time micro-interventions) acceptable, feasible, and efficacious for reducing anxiety at the time of scan procedures?

  • Which coping strategies are most effective for managing uncertainty about what results may show?

  • When is the optimal time to introduce a behavioral intervention with respect to scans?

Research Methods: Strengthening how Scanxiety Studies Are Conducted
Suggested Approaches Example Research Questions/Directions
Harmonize measures and examine psychometrics
  • How does scanxiety relate to close constructs such as fear of recurrence or progression, anticipatory anxiety, and state anxiety?

  • Is it sufficient to use existing state anxiety measures to index scanxiety? Or are there advantages to developing specific measures that reflect multiple elements or specific components of scanxiety?

  • Examine psychometrics of scanxiety measures

Improve description of follow-up care procedures
  • Strengthen descriptions of what typical follow-up procedures entail (e.g., exams, tests)

  • In studies of general anxiety, include questions about whether an upcoming scan or scan discussion is occurring

Detail time periods to include information on procedures and scan results delivery phases
  • Describe the length of time between assessment time points with respect to pre-scan, post-scan, and results delivery time points.

  • Report whether, when, and how results were delivered, and what they showed.

  • How do waiting periods and results delivery methods influence scanxiety?

  • How can clinicians or clinics structure the scan experience to help mitigate anxiety?

Explore innovative measurement strategies
  • Are daily diary and/or ecological momentary assessment approaches acceptable and feasible around the time of scans for older adults, those with advanced disease, and those on active treatment?

  • Do these approaches reveal fluctuations and individual differences not evident from one-time assessments?

Intervention Approaches: Developing and Testing Ways to Manage Scanxiety
Promising Approaches Example Research Directions/Intervention Targets
Screening to identify those experiencing or at higher risk for scanxiety
  • Use scan-specific measures to identify those with scanxiety

  • Prioritize at-risk individuals for interventions

Tailoring strategies to stressful time periods
  • Design interventions that address procedure-related and results-related components of scanxiety

  • Optimize strategies for each time period (e.g., pre-scan; awaiting results)

Behavioral / self-management strategies
  • Promote self-efficacy for coping with progression/recurrence

  • Bolster overall stress management skills (e.g., relaxation, pleasant activities)

  • Facilitate just-in-time strategies for distinct periods (e.g., during or directly before scans)

Clinic or system strategies
  • Reduce scan-to-results waiting time

  • Provide education/structure that promotes knowing what to expect for the procedure

  • Engage in shared decision-making about scans and results delivery