Table 1.
Characteristics | Patients (n = 97) |
---|---|
Age, mean ± SD, years | 67.5 ± 10.2 |
Males, n (%) | 55 (56.7%) |
Height, mean ± SD, cm | 168.1 ± 8.7 |
Weight, mean ± SD, kg | 73.8 ± 15.6 |
BMI, mean ± SD, kg·m−2 | 26.1 ± 4.9 |
BMI, categories, n (%) | |
Underweight | 4 (4.1%) |
Normal weight | 34 (35.1%) |
Overweight | 43 (44.3%) |
Obese | 16 (16.5%) |
Current smoker, n (%) a | 74 (83.1%) |
Tumour type, n (%) | |
Adenocarcinoma | 61 (62.9%) |
Adeno-squamous | 1 (1.0%) |
Large cell carcinoma | 2 (2.1%) |
Poorly differentiated | 3 (3.1%) |
Pleomorphic | 1 (1.0%) |
Squamous cell carcinoma | 29 (29.9%) |
Cancer stage, n (%) a | |
III | 15 (15.6%) |
IV | 81 (84.4%) |
Metastasis location, n (%) a | |
No metastasis | 14 (40%) |
Adrenal | 1 (2.9%) |
Bone | 6 (17.1%) |
Brain | 1 (2.9%) |
Liver | 2 (5.7%) |
Lymph node | 3 (8.6%) |
≥2 sites | 8 (22.9%) |
Treatment line, n (%) | |
First line treatment | 24 (24.7%) |
Second line treatment | 73 (75.3%) |
Treatment, n (%) | |
Atezolumab | 16 (16.5%) |
Nivolumab | 57 (58.8%) |
Pembrolizumab | 24 (24.7%) |
ECOG, n (%) a | |
0 | 49 (51.0%) |
1 | 34 (35.5%) |
2 | 12 (12.5%) |
3 | 1 (1.0%) |
Neutrophils, mean ± SD | 6.6 ± 4.4 |
Lymphocytes, mean ± SD | 1.5 ± 0.8 |
Haemoglobin, mean ± SD | 125.2 ± 20.4 |
Platelets, mean ± SD | 306.1 ± 122.0 |
Neutrophils-to-lymphocytes ratio, mean ± SD | 6.9 ± 11.6 |
PD-L1 levels, median (IQR), % | 60.0 (1.0 to 80.0) |
BMI, Body mass index; ECOG, Eastern Cooperative Oncology Group performance status; IQR, interquartile range; SD, standard deviation; a, missing data: current smoker, n = 8; cancer stage, n = 1; TNM, n = 16; metastasis location, n = 62; ECOG, n = 1.