AJCC	American Joint Committee on Cancer
BFS	breadth-first search
BCLC	Barcelona Clinic Liver Cancer
CI	confidence interval
DSBs	DNA double-strand breaks
EMT	epithelial-mesenchymal transition
HCC	hepatocellular carcinoma
IHC	immunohistochemical staining
KO	knockout
MET	mesenchymal-epithelial transition
NHEJ	non-homologous end joining
NGS	next-generation sequencing
OE	overexpressing
PVDF	polyvinylidene difluoride
PPI	protein–protein interaction
Ub	ubiquitin
USPs	ubiquitin-specific proteases
USP15	ubiquitin carboxyl-terminal hydrolase 15