Figure 4.

Rate of detection on ⁶⁸Ga-PSMA-11 PET/CT of lesions suspicious for prostate cancer in 115 men with BCR and very low PSA concentration (A,B) by PSA doubling time category (in months) (n = 83) and (C,D) by Gleason score of surgical specimen (n = 107). Panels (A,C) show numbers of patients with positive or negative scans, while panels (B,D) depict the overall suspicious lesion detection rate in percent (numbers atop the bars). Detection rates are significantly higher (p = 0.04) in patients with doubling time < 12 months (n = 67) than in their counterparts with doubling time > 12 months (n = 16). Additionally, detection rates are significantly higher (p = 0.01) in men with a Gleason score ≥ 7b (n = 62) than in those with a Gleason score of 6 or 7a (n = 45).