Table 2.
Active versus sham LF-rTMS for adolescent patients with FEDN depression: study-defined response and remission.
| Study | Treatment outcomes | Defination | Active LF-rTMS group | Sham stimulation group | Findings |
|---|---|---|---|---|---|
| (29) (China) | Study-defined response | NR | NR | NR | NA |
| Study-defined remission | NR | NR | NR | NA | |
| (31) (China) | Study-defined response | Reduction from baseline of ≥ 50% in the HAMD total score | 40.0% (12/30) | 13.3% (4/30) | P < 0.05 |
| Study-defined remission | Reduction from baseline of ≥ 75% in the HAMD total score | 13.3% (4/30) | 3.3% (1/30) | P > 0.05 | |
| (30) (China) | Study-defined response | Reduction from baseline of ≥ 50% in the HAMD total score | 46.7% (7/15) | 0% (0/15) | P < 0.05 |
| Study-defined remission | Reduction from baseline of ≥ 75% in the HAMD total score | 0% (0/15) | 0% (0/15) | P > 0.05 |
FEDN = first-episode and drug-naïve; HAMD = Hamilton depression rating scale; NR = not reported; LF-rTMS = low-frequency repetitive transcranial magnetic stimulation.