Table 1.
Changes in SLEB thickness and echogenicity in different pathologies.
| Year | Study Type | No. of Patients | Studied Disease | Ultrasound Frequency | Is the Level of SLEB Measuring Reported? | Is SLEB Present in Non Lesional Skin? | SLEB Changes | Reference |
|---|---|---|---|---|---|---|---|---|
| 2015 | Interventional study | 39 | Atopic dermatitis | 15–25 MHZ | Yes | Yes | DT | [8] |
| 2019 | Observational study | 10 | Atopic dermatitis | 15–25 MHZ | No | Yes | IT, DE | [10] |
| 2020 | Observational study | 18 | Atopic dermatitis | >25 MHZ | No | Yes | IT | [9] |
| 2012 | Case series | 160 | Skin aging | 15–25 MHZ | Yes | Yes | IT | [11] |
| 2015 | Interventional study | 28 | Skin aging | >25 MHZ | Yes | Not applied | IT, IE | [16] |
| 2015 | Interventional study | 22 | Skin aging (fillers with hyaluronic acid) | 15–25 MHZ | Yes | Not applied | IE | [14] |
| 2016 | Interventional study | 40 | Skin aging (chemical peels and radiofrequency) | >25 MHZ | Yes | Not applied | DT | [15] |
| 2017 | Case series | 31 | Skin aging | 15–25 MHZ | No | Yes | IT | [12] |
| 2019 | Observational study | 173 | Skin aging | 15–25 MHZ | No | Yes | IT, DE | [13] |
| 2021 | Interventional study | 12 | Aktinic keratosis and photoaging | >25 MHZ | No | Not applied | IT, DE | [17] |
| 2017 | Interventional study | 18 | Cutaneous lymphoma (Mycosis fungoides) | 15–25 MHZ | No | No | DT, IE | [18] |
| 2018 | Observational study | 3 | Cutaneous Lymphoma (Mycosis fungoides) | 15–25 MHZ | No | No | IT, DE | [19] |
| 2019 | Observational study | 10 | Cutaneous lymphoma | 15–25 MHZ | No | No | IT, DE | [20] |
| 2020 | Observational study | 26 | Cutaneous Lymphoma (Mycosis fungoides) | >25 MHZ | No | No | IT, DE | [22] |
| 2021 | Case series | 67 | Cutaneous lymphoma (Mycosis fungoides), psoriasis/eczema | >25 MHZ | No | Not applied | IT, DE | [21] |
| 2012 | Observational study | 87 | Diabetic foot | >25 MHZ | Yes | Yes | IT | [27] |
| 2016 | Observational study | 30 | Arm lymphedema | 1–14 MHZ | Yes | Not applied | IT | [31] |
| 2019 | Interventional study | 50 | Vaginal rejuvenation | 15–25 MHZ | Yes | No | IT, DE | [25] |
| 2019 | Observational study | 21 | Lichen planus | >25 MHZ | No | Yes | IT | [28] |
| 2020 | Interventional study | 9 | Venous leg ulcer (cold atmospheric plasma treatment) | 15–25 MHZ | Yes | Yes | IT | [26] |
| 2021 | Observational study | 5 | Granuloma faciale | 15–25 MHZ | No | No | IT, DE | [29] |
| 2021 | Case series | 4 | Talar callosity | 1–14 MHZ | Yes | Yes | DT, IE | [30] |
| 2021 | Interventional study | 46 | Psoriasis (D-chiro-inositol treatment) |
15–25 MHZ | No | Yes | IT, DE | [23] |
| 2022 | Observational study | 71 | Psoriasis | >25 MHZ | Yes | Yes | IT, DE | [24] |
IT, increased thickness (measured in mm, perpendicular to skin surface), DT, decreased thickness (measured in mm, perpendicular to skin surface), IE, increased echogenicity, DE, decreased echogenicity.