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. 2023 Feb 28;12(5):768. doi: 10.3390/cells12050768

Figure 6.

Figure 6

Effects of GM-080 consumption in OVA-specific antibodies or OVA-induced IL-5 production in an OVA-induced AHR mouse model. (A–C) Mice sera were collected 2 days after final theOVA challenge, and the presence of OVA-specific IgE (A), IgG1 (B), and IgG2a (C) was determined using ELISA. (D–F) Splenocytes were collected 2 days after the final OVA challenge and then seeded into a 48-well-plate at a density of 5 × 106 cells/well to determine IL-5 production without treatment (D) or after treatment with 2 µg/mL ConA (E) or 100 µg/mL OVA (F). NC, nontreated control; H2O, H2O gavage; LP-L, GM-080 at 2 × 106 CFU/mouse/day through gavage; LP-H, GM-080 at 1 × 107 CFU/mouse/day through gavage. * p < 0.05, ** p < 0.01.