Table 2.
Prognostic factors associated with overall survival in children with localized or metastatic disease.
| Localized | Metastatic | Overall | |||||||
|---|---|---|---|---|---|---|---|---|---|
| Variables | Raised CRP | Normal CRP | p-Value | Raised CRP | Normal CRP | p-Value | Raised CRP | Normal CRP | p-Value |
| n. Patients (%) | 37 | 60 |
p = 0.025
(Proportion Z-Test) |
28 | 12 |
p = 0.017
(Proportion Z-Test) |
65 (43.0) | 72 (47.7) |
p = 0.608
(Proportion Z-Test) |
| Gender n. (%) |
p = 0.238
(Fisher’s Exact Test) |
p = 1.000
(Fisher’s Exact Test) |
p = 0.249
(Fisher’s Exact Test) |
||||||
| Male | 30 (81.1) | 41 (68.3) | 21 (75.0) | 9 (75.0) | 51 (78.5) | 50 (69.4) | |||
| Female | 7 (18.9) | 19 (31.7) | 7 (25.0) | 3 (25.0) | 14 (21.5) | 22 (30.6) | |||
| Mean age (min-max) |
13.4 (3.0–18.0) |
12.4 (3.0–18.0) |
p = 0.224
(t-Test) |
14.5 (6.0–18.0) |
12.3 (6.0–18.0) |
p = 0.055
(t-Test) |
13.8 (3.0–18.0) |
12.3 (3.0–18.0) |
p = 0.021
(t-Test) |
| n. Tumor location (%) |
p = 0.020
(Fisher’s Exact Test) |
p = 0.152
(Fisher’s Exact Test) |
p < 0.001
(Fisher’s Exact Test) |
||||||
| Extremities | 24 (64.9) | 52 (86.7) | 15 (53.6) | 10 (83.3) | 39 (60.0) | 62 (86.1) | |||
| Trunk | 13 (35.1) | 8 (13.3) | 13 (46.4) | 2 (16.7) | 26 (40.0) | 10 (13.9) | |||
| Tumor size |
p = 0.004
(Fisher’s Exact Test) |
p = 0.027
(Fisher’s Exact Test) |
p < 0.001
(Fisher’s Exact Test) |
||||||
| >200 mL | 16 (43.2) | 10 (16.7) | 22 (78.6) | 5 (41.7) | 38 (58.5) | 15 (20.8) | |||
| <200 mL | 18 (48.6) | 46 (76.7) | 3 (10.7) | 5 (41.7) | 21 (32.3) | 51 (70.8) | |||