ALSFRS-R	Revised Amyotrophic Lateral Sclerosis Functional Rating Scale
ADM	abductor digiti minimi
ALS	amyotrophic lateral sclerosis
ALS-bci	ALS with cognitive and behavioral impairment
ALS-bi	ALS with behavioral impairment
ALS-ci	ALS with cognitive impariment
APB	abductor pollicis brevis
APBD	adult polyglucosan body disease
AR	androgen receptor
ASO	antisense oligonucleotide
ATXN2	Ataxin 2
Aβ	Amyloid β
bFGF	basic fibroblast growth factor
C9orf72	chromosome 9 open reading frame 72
CD83	cluster of differentiation 83
CHI3L1	chitinase-3-like protein 1
CHI3L2	chitinase-3-like protein 2
CHIT1	chitotriosidase 1
CJD	Creutzfeld-Jakob disease
CK	creatine kinase
CLP	chitinase-like proteins
CSA	cross-sectional areas
CSF	cerebrospinal fluid
CST	corticospinal tract
cTnT	cardiac troponin T
CXCL1	chemokine (C-X-C motif) ligand 1
CXCL2	chemokine (C-X-C motif) ligand 2
DTI	diffusion tensor imaging
DTR	deep tendon reflex
ECAS	Edinburgh Cognitive and Behavioral ALS Screen
ED	electrodiagnostic
EMG	electromyography
FAB	Frontal Assessment Battery
FAS	flail-arm-syndrome
FDG-PET	[18F]Fluorodeoxyglucose-PET
FDI	first dorsal interosseus
FLS	flail-leg-syndrome
FOSB	FBJ murine osteosarcoma viral oncogene homolog B
FTD	Frontotemporal dementia
FUS	fused-in sarcoma
GWAS	Genome-wide association studies
HRE	hexanucleotide (G4C2)n repeat expansion
HSP	hereditary spastic paraparesis
IL-18	interleukin-18
IL-8	interleukin-8
iPSCs	induced pluripotent stem cells
LMN	lower motor neurons
MCP-1	monocyte chemoattractant protein-1
MiToS	Milano Torino Staging System
MMI	mild motor impairment
MMN	multifocal motor neuropathy
MMSE	Mini Mental State Assessment
MND	motor neuron disease
MoCa	Montreal Cognitive Assessment Test
MRI	magnetic resonance imaging
MS	multiple sclerosis
Nf	neurofilaments
NfL	neurofilament light chain
NGS	next-generation sequencing
PET	positron emission tomography
PLS	primary lateral sclerosis
PMA	progressive muscular atrophy
pNfH	phosphorylated neurofilament heavy chain
Poly-GP	arginine containing dipeptide repeat polymers
PRS	polygenic risk scores
pTau	phosphorylated Tau
ROADS	Rasch overall ALS disability scale
sAPPβ	soluble amyloid precursor protein
SBMA	spinal and bulbar muscular atrophy
SMA	spinal muscular atrophy
SOCS3	suppressor of cytokine signaling 3
SOD1	superoxide dismutase 1
SPP1	secreted Phosphoprotein 1
TARDBP	TAR DNA binding protein
TDP-43	transactive response DNA binding protein 43
TNF-α	tumor necrosis factor
TSPO	18pkD translocator protein
t-Tau	total Tau
UMN	upper motor neurons
Vn	vagus nerve