Table 3.

Compounds used for removal of Mycoplasma from contaminated cell cultures.

Compound	Composition
BM-Cyclin	Tiamulin fumarate (a Macrolide) and Minocycline hydrochloride (a Tetracycline)
Ciprobay	Ciprofloxacin (a Quinolone)
Mycoplasma Removal Agent (MRA)	4-oxo-quinoline-3-carboxylic acid derivative (a Quinolone)
Plasmocin	Contains two bactericidal components (a macrolide acting on the protein synthesis machinery by inhibiting the 50S ribosomal subunit and a fluoroquinolone inhibiting the DNA gyrase)
Baytril	Enrofloxacin (a Quinolone, inhibitor of DNA gyrase)
Zagam	Sparfloxacin (a Quinolone, inhibitor of DNA gyrase)
MycoZap	Ready-to-use combination of a not-disclosed surface-active antimicrobial peptide (MycoZap reagent 1) and a not-disclosed antibiotic (MycoZap reagent 2).
MycoRAZOR	Ready-to-use antibiotic mixture prepared in PBS acting against a large variety of mycoplasma by acting on the protein synthesis mechanism by interfering with the ribosome translation of the mycoplasms as well as with their transcription apparatus.
Normocin	Three antibiotics. Two of these compounds act on mycoplasmas, Gram-positive, and Gram-negative bacteria by blocking DNA and protein synthesis. The third compound eradicates fungi, including yeasts, by disrupting ionic exchange through the cell membrane.
Fungin	The soluble form of Pimarcin, a polyene that attacks yeasts, molds, and fungi by disrupting ionic exchange through the cell membrane.
Plasmocure	It contains two bactericidal components belonging to different antibiotic families. The first antibiotic binds to the 50S subunit of the ribosome and blocks peptidyltransferase activity, while the second antibiotic binds to isoleucyl-tRNA synthetase, thereby halting the incorporation of isoleucine into bacterial proteins.
Normocure	Contains three bactericidal components belonging to different antibiotic families that inhibit DNA and protein synthesis and disrupt membrane integrity by targeting structures that are absent in eukaryotic cells.