Figure 1.

The histological subtypes, common and stem cell-associated markers of breast cancer. The top panel shows representative histological micrographs stained with hematoxylin-eosin of lobular-type (a) and ductal-type breast carcinoma (b). Representative images of the expression of the first immunohistochemical biomarkers that have laid the foundations for the classification of the BC subtypes, the estrogen receptor (c), the progesterone receptor (d), and the human epidermal growth factor receptor 2 or HER2 (e). The bottom panel shows the expression of the breast cancer stem cell-associated biomarkers CD44 (f), and CD133 (g). Original magnification 100×.