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. 2001 Dec;21(24):8490–8503. doi: 10.1128/MCB.21.24.8490-8503.2001

FIG. 5.

FIG. 5

Addition of 35 bp of upstream sequence to SURE-807 restores slow fiber-restricted enhancer activity. Slow and fast muscles from founders of three independent transgenic lines harboring TnIs95.SURE-827 (A) and three lines of TnIs95.SURE-842 as well as two lines of TnIs95.SURE-857 (B) expressing the luciferase reporter were analyzed for reporter activity. SURE-827 includes the CAGG motif but not the BLM, whereas SURE-842 and SURE-857 contain both motifs. All transgenic lines selectively expressed luciferase in skeletal muscle.