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. 2023 Mar 6;20(5):4655. doi: 10.3390/ijerph20054655

Table 1.

Studies related to the legalization of medical cannabis: country, sample, and most relevant variables.

Article Country (States)/Years Sample Size Study Group Variables Data Collected/Detection Method
Jones et al. (2019) [22] U.S. (Arizona) (2008–2014) THC+: N = 2590
Alcohol+: N = 5266
THC+ and alcohol: N = 1086
Injured driver Use of cannabis, alcohol, or both substances after a traffic accident. Pre-legalization: January 2008–April 2011; Post-legalization: April 2011–December 2014. Urine drug screens for cannabis metabolites and BAC.
Wadsworth and Hammond (2019) [23] Canada, England, and U.S. July, 2017 Canada: N = 4008
England: N = 3970
U.S.: N = 4086
Youth Use, access, perceptions of harm and driving after cannabis and/or alcohol use. Sociodemographic variables. Self-report completed using web-based surveys.
Steinemann et al. (2018) [24] U.S. (Hawaii) (1993–2015) Pre-legalization (1993–2000):
N = 560; THC+ 31 (6%). Post-legalization (2001–2015): N = 1018.
THC+ 151(15%).
Drivers killed THC+ and alcohol in drivers. Pre- and post-legalization. FARS.
Urine toxicology and blood drug test.
Sevigny (2018) [25] U.S. (1993–2014) Nearly 1.2 million drivers involved in fatal traffic accidents.
THC+ 8.8% BAC ≥ 0.08 = 20.1%.
Drivers Presence of THC, other illicit drugs, and alcohol.
Variables related to cannabis regularization.
Contextual and control variables.
FARS. Blood drug test.
Santaella-Tenorio et al. (2017) [26] U.S. (50 states) (1985–2014) N = 1,220,610. Deaths in traffic accidents Fatal traffic accidents. Age 14–24, 25–44, and 45< years.
Date MML by State. Dispensaries.
FARS. Blood drug test.
Masten and Guenzburger (2014) [27] U.S. (14 states that have legalized cannabis and 37 jurisdictions without MCL) (1992–2009) Drivers involved in fatal crashes: THC+
N = 19,977.
Drivers Presence of THC in drivers involved in fatal traffic accidents. FARS. Blood and/or urine drug test.
Salomonsen-Sautel et al. (2014) [28] U.S. (Colorado and 34 states without MCL) (1994–2011) Proportions of drivers involved in fatal crashes. Colorado: THC+ between 4.5% to 10%. States without MCL: THC+ between 1.1% to 4.1% Drivers THC+ or alcohol BAC ≥ 0.08. Pre-commercialization,
June 1994–July 2009; Post-commercialization,
July 2009–2011.
FARS. Blood and/or urine drug test.
Anderson et al. (2013) [29] U.S. (1990–2010) Age: 15–60< years old.
20.48 (7.15)
Fatalities per 100,000 people Fatal traffic accidents. Sociodemographic variables.
Control states and MCL states.
FARS. Blood drug test.

Note: BAC (blood alcohol concentration), FARS (Fatality Analysis Reporting System database), and MCL (medical cannabis legalization).