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. 2023 Mar 6;20(5):4655. doi: 10.3390/ijerph20054655

Table 5.

Studies related to the legalization of recreational and medicinal cannabis and its decriminalization: country, sample, and most relevant variables.

Article Country (State)/Years Sample Size Study Group Variables Data Collected/Detection Method
Benedetti et al. (2021) [42] U.S. (2013–2017). CR illegal: N = 10,294 drivers; CR legal:
N = 876 drivers. MC illegal: N = 5782 drivers;
MC legal: N = 5388 drivers.
Drivers Marijuana use while driving in the last year.
States with the legalization of MM, MM, and MR or no legalization of both. Marijuana policy.
Sociodemographic variables. TSCI is a nationally representative annual survey.
Self-reported.
Kruse et al. (2021) [44] U.S. (Arizona, California, Ohio, Oregon, New Jersey, and Texas)
Pre-legalization: 2006–2012.
Post-legalization: 2013–2018.
Not specified Patients with trauma Vehicle collisions. THC-positive patients and alcohol-positive patients > 0.08 g/dL). Data from different universities. Urine and blood analysis.
Woo et al. (2019) [8] U.S. (Washington) (2008–2016). N = 10,155 accidents and 5931 drivers. THC > 5.00 = 4.2%, THC <5 = 3.1%, Clean 92.6%. BAC > 0.08 = 19.2%, BAC <0.08 = 3.5%, Clean 77.3%. Drivers Fatal accidents. Speeding and driver error. THC (<5 ng/mL in blood or >5 ng/mL). Carboxy-THC. Alcohol (0.08 less or more). Control variables. Environmental Contexts. FARS. Blood tested.
Keric et al. (2018) [45] U.S. (Texas and California) (2006–2012). N = 127 Surgeons. UTHSCSA center: patients traffic accidents N = 7171. Alcohol+ 21%, THC+ 4%, alcohol and THC+ 3%. Center in California:
N = 16,084, alcohol+ 50%, THC+ 23%, alcohol and THC+ 7%.
Surgeons and patients Alcohol (>0.08 g/dL). Marijuana (>50 ng/mL in Texas and >100 ng/mL in California). Injuries related to traffic accidents. Decriminalization in CA in 2010. Electronic survey completed by the members of the American Association for the Surgery of Trauma. Trauma center registries at The University of California Irvine and UTHSCSA.
Lee et al. (2018) [43] U.S. (16 states) (2008–2015). Number of accidents involving cannabis in states with law changes. Before, N = 1458. After, N = 938. Drivers Types of states according to cannabis legalization and decriminalization laws. FARS.
Hamzeie et al. (2017) [46] U.S. (50 states and District of Columbia) (2010–2014). THC+: N = 9301 drivers
THC−: N = 65,332 drivers
Drivers States with legalization and decriminalization laws and states with no such laws. Driver, accident, and vehicle characteristics. THC+ and THC−. FARS.
Pollini et al. (2015) [47] U.S. (California). (2008–2012). (2008–2010): N = 1718; THC+ N = 203
(2011–2012): N = 1142; THC+ N = 175
Drivers Detection of cannabis use in drivers involved in traffic accidents. Decriminalization period: 2011–2012. No decriminalization period: 2008–2010. FARS.
Couper and Peterson (2014) [48] U.S. (Washington, D.C.) (2009–2013) N = 25,179, age 14–85 years old. Median age 25 years pre-legalization and 26 years post-legalization. Drivers Detection of THC consumption. (Pre-legalization THC+ 0.2 ng/mL, carboxy-THC of 0.10 ng/mL). Pre-legalization: 2009–2012. Post-legalization: 2013. Blood tested

Note: FARS (Fatality Analysis Reporting System database).