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. 2023 Feb 22;24(5):4351. doi: 10.3390/ijms24054351

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© 2023 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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Forest plot demonstrating the effect of umbilical cord blood-derived cell therapy on neuroinflammation (A) TNF-α; (B) IL-6; (C) IL-1β; (D) IL-10. Umbilical cord blood-derived cell therapy significantly decreased neuroinflammation as measured by TNF-α (p < 0.0001), IL-6 (p < 0.01) and IL-1β (p = 0.001). Abbreviations: admin, administration; ICV, intracerebroventricular; IV, intravenous; PCB, preterm cord blood; TCB, term cord blood; UCBC, umbilical cord blood cells.

Forest plot demonstrating the effect of umbilical cord blood-derived cell therapy on neuroinflammation (A) TNF-α; (B) IL-6; (C) IL-1β; (D) IL-10. Umbilical cord blood-derived cell therapy significantly decreased neuroinflammation as measured by TNF-α (p < 0.0001), IL-6 (p < 0.01) and IL-1β (p = 0.001). Abbreviations: admin, administration; ICV, intracerebroventricular; IV, intravenous; PCB, preterm cord blood; TCB, term cord blood; UCBC, umbilical cord blood cells.