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. 2023 Feb 21;24(5):4272. doi: 10.3390/ijms24054272

Figure 2.

Figure 2

Functional analysis of target gene signatures regulated by hsa-miR-101-3p and hsa-miR-490-3p. (a) Overlapping target genes of hsa-miR-101-3p and hsa-miR-490-3p predicted by the ENCORI tool (https://starbase.sysu.edu.cn/ accessed on 12 January 2022) and CLIP-seq data. (b) Validation of the hsa-miR-101-3p and hsa-miR-490-3p target genes by miRTarBase. (c) Top 5 Gene Ontology classifications of the hsa-miR-101-3p target genes in biological processes (left), molecular functions (middle), and cellular components (right). (d) Top 5 Gene Ontology classifications of the hsa-miR-490-3p target genes in biological processes (left), molecular functions (middle), and cellular components (right). (e) Pathway enrichment analysis of the hsa-miR-101-3p target genes using KEGG 2021 Human and MSigDB Hallmark 2020. (f) Pathway enrichment analysis of the hsa-miR-490-3p target genes using KEGG 2021 Human and MSigDB Hallmark 2020.