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Normal histology of PPEF-2−/− mice at 1 year and 2×KO mice at 3 months. Sections (10 μm) of eyes from 12-month-old PPEF-2−/− mice and 3-month-old 2×KO mice were stained with toluidine blue. OS, photoreceptor outer segments; IS, photoreceptor inner segments; ONL, outer nuclear layer; OPL, outer plexiform layer; INL, inner nuclear layer; IPL, inner plexiform layer; and GCL, ganglion cell layer. Scale bar in lower right of each panel corresponds to 25 μm.
