. 2023 Feb 26;24(5):4568. doi: 10.3390/ijms24054568

Table 2.

Comparison of KEGG metabolism pathways of fecal microbiota between week 0 and week 24 post-treatment in psoriasis.

Treatment	KEGG Pathway	Week 0	Week 24	p-Value
IL-23 inhibitor	Lipid metabolism
	Fatty acid biosynthesis [PATH:ko00061]	0.00864	0.008873	0.002367
	00071 Fatty acid degradation [PATH:ko00071]	0.004989	0.005184	0.04726
	00565 Ether lipid metabolism [PATH:ko00565]	0.000109	0.000132	0.03842
	00592 alpha-linolenic acid metabolism [PATH:ko00592]	5.31 × 10⁻⁵	6.27 × 10⁻⁵	0.04265
	Energy metabolism
	00195 Photosynthesis [PATH:ko00195]	0.005238	0.005149	0.02341
	00680 Methane metabolism [PATH:ko00680]	0.01616	0.01592	0.007612
	00710 Carbon fixation in photosynthetic organisms [PATH:ko00710]	0.01162	0.01144	0.002367
	Amino acid metabolism
	00220 Arginine biosynthesis [PATH:ko00220]	0.01214	0.01188	0.01205
	00270 Cysteine and methionine metabolism [PATH:ko00270]	0.02268	0.0225	0.04049
	00480 Glutathione metabolism [PATH:ko00480]	0.003758	0.003977	0.0221
	Carbohydrate metabolism
	00051 Fructose and mannose metabolism [PATH:ko00051]	0.01362	0.01336	0.0106
	00562 Inositol phosphate metabolism [PATH:ko00562]	0.001421	0.001496	0.03272
	00332 Carbapenem biosynthesis [PATH:ko00332]	0.001633	0.001594	0.04971
IL-17 inhibitor	00300 Lysine biosynthesis [PATH:ko00300]	0.01177	0.01159	0.03423
	00901 Indole alkaloid biosynthesis [PATH:ko00901]	1.91 × 10⁻⁶	2.50 × 10⁻⁶	0.03036