Table II.

Primary outcomes

Comparison	Endpoint in treatment	Endpoint in control	PSM		LR
			OR (CI)	p	OR (CI)	p
Spironolactone (n = 16,324)
Ventilation	1,212 (7.4%)	1,459 (8.9%)	0.82 (0.75-0.88)	<0.001	0.78 (0.73-0.83)	<0.001
Mortality	521 (3.2%)	592 (3.6%)	0.88 (0.78-0.99)	0.033	0.85 (0.78-0.93)	<0.001
Vaccination (n = 59,387)
Ventilation	2,939 (4.9%)	3,974 (6.7%)	0.72 (0.69-0.76)	<0.001	0.68 (0.66-0.71)	<0.001
Mortality	1,138 (1.9%)	1,811 (3.0%)	0.62 (0.58-0.67)	<0.001	0.61 (0.57-0.64)	<0.001