Table 1.
18F-FES estrogen receptor density in regions-of-interest by menopausal stage
| Pre-menopause | Peri-menopause | Post-menopause | |
|---|---|---|---|
| Amygdala | 1.011 (0.976, 1.045) | 1.050 (1.025, 1.075) | 1.055 (1.022, 1.089) |
| Anterior cingulate | 1.164 (1.118, 1.211) | 1.166 (1.132, 1.200) | 1.222 (1.177, 1.267) |
| Caudate | 1.109 (1.057, 1.161) | 1.153 (1.116, 1.191) | 1.167 (1.119, 1.219) |
| Hippocampus | 1.212 (1.174, 1.249) | 1.238 (1.21, 1.265) | 1.251 (1.214, 1.288) |
| Hypothalamus | 0.905 (0.864, 0.945) | 0.972 (0.943, 1.001) | 1.009 (0.969, 1.048) |
| Middle frontal gyrus | 1.041 (1.007, 1.075) | 1.075 (1.050, 1.100) | 1.123 (1.088, 1.157) |
| Nucleus Accumbens | 0.945 (0.903, 0.987) | 0.999 (0.968, 1.029) | 1.066 (1.025, 1.107) |
| Orbitofrontal gyrus | 1.049 (1.010, 1.087) | 1.088 (1.060, 1.116) | 1.133 (1.095, 1.170) |
| Pituitary | 3.729 (3.208, 4.25) | 3.822 (3.444, 4.200) | 4.045 (3.536, 4.554) |
| Putamen | 1.282 (1.226, 1.339) | 1.281 (1.24, 1.322) | 1.297 (1.242, 1.352) |
| Thalamus | 1.309 (1.262, 1.355) | 1.309 (1.275, 1.343) | 1.353 (1.308, 1.399) |
Means and 95% confidence intervals by menopause status, adjusting for age. 18F-FES measures are standardized uptake value ratios (SUVR) to cerebellum.