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. 2023 Feb 26;24(5):4585. doi: 10.3390/ijms24054585

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© 2023 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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Effects of perinatal exposure to BPA on inflammatory mediator and apoptosis markers in livers from female PND6 offspring. (A,B) mRNA and protein expressions of IL1β (interleukin-1-β). (C,D); mRNA and protein expression of AIF (apoptosis-inducing factor). (E) mRNA of BAX (Bcl-2-associated X protein). (F,G) Protein expressions of BCL-2 (B-cell lymphoma) and BCL-XL (B-cell lymphoma-extra large). (H) Representative images of the Western blot results of the different proteins studied. Data represent mean ± SD. For mRNA, n = 12 control PND6 offspring; n = 12 LBPA PND6 offspring; n = 12 HBPA PND6 offspring (three replicates for each gene). For protein, n = 5 rats per experimental group. Statistical significance was determined by one-way ANOVA. * p < 0.05.