Skip to main content
. 2023 Mar 6;24(5):5020. doi: 10.3390/ijms24055020

Figure 2.

Figure 2

Predictors of time to major cardiovascular event (MACE). (A) Survival curve for time until MACE accordingly to peritoneal membrane status. (B) Multivariate Cox model that includes peritoneal fibrosis as an indicator of the membrane status adjusted for age, nutritional status, frailty and PAD. (C) Multivariate Cox model similar to B, but using α-Klotho cutoff as a surrogate of membrane fibrosis. (D) Multivariate Cox model using levels of circulating α-Klotho as surrogate of membrane fibrosis and using the antiplatelet therapy as an indicator of atherosclerotic arterial disease. (E) Survival curves for time until MACE according to α-Klotho cutoff of 742 pg/mL. GFR—glomerular filtration; PAD—peripheral arterial disease; CHD—coronary heart disease; HF—heart failure; nPCR—normalized protein catabolic rate.