Table 3.
Agreement between MMR IHC status and MSI PCR testing.
| MSI PCR | |||||
|---|---|---|---|---|---|
| All EC (n = 99) | POLEwt EC (n = 83) | ||||
| MSI-high | MSS | MSI-high | MSS | ||
| MMR IHC status | MMRd | 31 | 8 | 25 | 7 |
| MMRp | 3 | 57 | 3 | 48 | |
| Sensitivity % | 91.2 (95% CI: 76.3–98.1) * |
89.3 (95% CI: 71.8–97.7) * |
|||
| Specificity % | 87.7 (95% CI: 77.2–94.5) * |
87.3 (95% CI: 75.5–94.7) * |
|||
| Accuracy % | 88.9 (95% CI: 81.0–94.3) * |
88.0 (95% CI: 79.0–94.1) * |
|||
| PPV % | 79.5 (95% CI: 63.5–90.7) * |
78.1 (95% CI: 60.0–90.7) * |
|||
| NPV % | 95.0 (95% CI: 86.1–99.0) * |
94.1 (95% CI: 83.8–98.8) * |
|||
* Exact Cis.