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Resveratrol’s viability inhibition and chemosensitisation to 5-FU via β1-integrin receptors in HCT-116/HCT-116R cells shown by MTT assay. X-axis: HCT-116 (A) and HCT-116R (B) cells, grown in alginate, were left untreated as basal control (Ba.Co.), as TME control (TME) or CRC cells in TME were treated with 5-FU (2 nM), resveratrol (5 µM) or β1-SO/β1-ASO (0.5 µM), alone or combined. Y-axis: viable CRC cells at 550 nm. Compared to TME control: p < 0.05 (⋆) and p < 0.01 (⋆⋆).
