Table 5.
Analysis of microRNA polymorphisms for severe hematologic toxicity.
| ID SNV | Severe Hematologic Toxicity | p-Value a | OR (CI 95%) b | |
|---|---|---|---|---|
| Yes | No | |||
| EFNA1_rs12904 | ||||
| AA | 4 (15.4) | 14 (41.2) | 0.037 | AA vs. others |
| AG | 16 (61.5) | 13 (38.2) | ||
| GG | 6 (23.1) | 7 (20.6) | 0.26 (0.73–0.92) | |
| MIR499A_rs3746444 | ||||
| AA | 4 (16.0) | 1 (3.2) | 0.025 | GG vs. others |
| AG | 17 (68.0) | 16 (51.6) | ||
| GG | 4 (16.0) | 14 (45.2) | 0.23 (0.06–0.83) | |
| MIRLET7A1_rs10739971 | ||||
| AA | 10 (52.6) | 15 (41.7) | 0.040 | GG vs. others |
| AG | 7 (36.8) | 7 (19.4) | ||
| GG | 2 (10.5) | 14 (38.9) | 0.18 (0.04–0.93) | |
ap-value < 0.05; b Simple logistic regression.