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The diagram shows the influence of the tumor microenvironment on hypothermia and the effects of photothermal therapy mediated by polydopamine-based nanoparticles. A large amount of gold nanoparticles accumulates in cancer cells, which causes a photothermal effect in response to near-infrared light (NIR) and reactive oxygen species (ROS), ultimately inducing apoptosis and necrosis of cancer tissue.
