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Potential Zymosan and empagliflozin interactions with Dectin-1. (A) Zymosan may interact via multiple hydrogen bonds (dotted yellow lines) with H126, K128, S129, Y131, N159, and E241 amino acid residues of Dectin-1. (B) Empagliflozin has a moiety identical to Zymosan. (C) The Zymosan-like moiety may enable Empagliflozin to interact with Y131 and N159 amino acid residues of Dectin-1 via H-bond formation.
