Table 1.
Compounds | a CC50 (μM) | H1N1 (PR8) | H5N1 | H3N2 | |||
---|---|---|---|---|---|---|---|
b EC50 (μM) | c SI | b EC50 (μM) | c SI | EC50 (μM) | c SI | ||
G-rk1 | 34.8 | 6.2 | 5.6 | 10.4 | 3.3 | 13.5 | 2.6 |
G-rg5 | >40.0 | 8.2 | >5.0 | 14.8 | >2.8 | 11.5 | >3.6 |
a CC50 is a concentration needed to cut normal cell viability by 50%; b EC50 is a concentration needed to protect 50% of cells from IAV infection; c SI (selectivity index) is the ratio of CC50 to EC50.