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. 2023 Mar 4;24(5):4967. doi: 10.3390/ijms24054967

Table 1.

Cellular toxicity and inhibitory effects of G-rk1 and G-rg5 against IAV in A549 cells.

Compounds a CC50 (μM) H1N1 (PR8) H5N1 H3N2
b EC50 (μM) c SI b EC50 (μM) c SI EC50 (μM) c SI
G-rk1 34.8 6.2 5.6 10.4 3.3 13.5 2.6
G-rg5 >40.0 8.2 >5.0 14.8 >2.8 11.5 >3.6

a CC50 is a concentration needed to cut normal cell viability by 50%; b EC50 is a concentration needed to protect 50% of cells from IAV infection; c SI (selectivity index) is the ratio of CC50 to EC50.