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. 2023 Feb 24;24(5):4487. doi: 10.3390/ijms24054487
5-FU 5-Fluorouracil
ABC ATP-Binding Cassette
BER Base-Excision Repair
CDA Cytidine Deaminase
CDP Cytidine Diphosphate
CDTD Deoxycytidine Monophosphate Deaminase
CSCs Cancer Stem-Like Cells
dCDA Deoxycytidine Deaminase
dCDP Deoxycytidine Diphosphate
dCK Deoxycytidine Kinase
dCTP Deoxycytidine Triphosphate
DDDs DNA-Damaging Drugs
DDRs DNA-Damage Responses
dFdC Gemcitabine
dFdCDP Gemcitabine Diphosphate
dFdCMP Gemcitabine Monophosphate
dFdCTP Gemcitabine Triphosphate
dFdU 2′,2′-Difluorodeoxyuridine
dFdUMP 2′,2′-Difluorodeoxyuridine Monophosphate
dFdUTP 2′,2′-Difluorodeoxyuridine Triphosphate
DFDCDP Difluorodeoxycytidine Diphosphate
DFDCMP Difluorodeoxycytidine Monophosphate
DFDCTP Difluorodeoxycytidine Triphosphate
DNA Deoxyribonucleic Acid
DPD Dihydropyrimidine Dehydrogenase
dTMP Deoxythymidine Monophosphate
EMT Epithelial-to-Mesenchymal Transition
ER Endoplasmic Reticulum
FDUMP Fluorodeoxyuridine Monophosphate
Gem Gemcitabine
GOF Gain Of Functions
GSIs Gamma-Secretase Inhibitors
GSH Glutathione
HR Homologous Recombination
IC50 Half-Maximal Inhibitory Concentration
IDH1 Isocitrate Dehydrogenase 1
JAK/STAT3 Janus kinase/Signal Transducers and Activators of Transcription
MHC Major Histocompatibility Complex Class
MVP Major Vault Protein
NDPK Nucleoside Diphosphate Kinase
NER Nucleotide Excision Repair
NHEJ Non-Homologous End-Joining
NMPK Nucleoside Monophosphate Kinase
OATP Organic Anionic Transporter
OCT Organic Cation Transport
ROS Reactive Oxygen Species
RNA Ribonucleic Acid
RR Ribonucleotide Reductase
Ser Serine
TAMs Tumor-Associated Macrophages
TME Tumor Microenvironment
TK1 Thymidine Kinase 1
TS Thymidine Synthase
VDR Vitamin D Receptor
VRAC Volume-Regulated Anion Channel