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Correlation between KRAS gene and CTLA-4 expression in CTCs. (A) The mRNA expression level of CTLA-4 correlated positively with KRAS (r = 0.6878, p = 0.0002). r; coefficient correlation value (Spearman’s rank test). (B) The mRNA expression levels of CTLA-4 in CTCs and PBMCs from patients with CRC according to the KRAS mutation status of the primary tumour.
