Table 1.
Demographics and clinical characteristics for study population.
| Variables | Total (n = 57) | Case (n = 12) | Control (n = 45) | p |
|---|---|---|---|---|
| Gestational age, weeks a | 24.6 (23.4, 25.4) | 25.3 (24.4, 26.1) | 24.6 (23.3, 25) | 0.119 b |
| Birth weight, g a | 620 (540, 730) | 680 (620, 835) | 610 (520, 730) | 0.106 b |
| Male sex | 33 (58%) | 5 (42%) | 28 (62%) | 0.200 c |
| Apgar score a | ||||
| At 1 min | 4 (3, 5) | 4 (2.5, 5.5) | 4 (3, 5) | 0.584 b |
| At 5 min | 7 (6, 8) | 7 (5, 8) | 7 (6, 9) | 0.301 b |
| Small for gestational age | 13 (23%) | 2 (17%) | 11 (24%) | 0.713 c |
| Chorioamnionitis | 28 (49%) | 5 (42%) | 23 (51%) | 0.561 c |
| Premature rupture of membrane | 17 (30%) | 3 (25%) | 14 (31%) | 1.000 c |
| Antenatal corticosteroid use | 56 (98%) | 11 (92%) | 45 (100%) | 0.211 c |
| High-grade intraventricular hemorrhage | 21 (37%) | 3 (25%) | 18 (40%) | 0.504 c |
| Neonatal sepsis | 52 (91%) | 8 (67%) | 44 (98%) | 0.006 c |
| Acute kidney injury | 22 (39%) | 4 (33%) | 18 (40%) | 0.841 c |
| NSAIDs use | 12 (21%) | 4 (33%) | 8 (18%) | 0.254 c |
| HFOV support | 32 (56%) | 5 (42%) | 27 (60%) | 0.418 c |
| Preoperative pletelet counts, ×109/L d | 154.1 ± 130.0 | 235.3 ± 161.5 | 132.4 ± 112.7 | 0.057 b |
| Postnatal age at laparotomy, days a | 21 (14, 36) | 30 (22, 45.5) | 20 (12, 31) | 0.018 b |
Unless otherwise indicated, data are the number of patients, with percentages in parentheses. HFOV, high-frequency oscillatory ventilation. a Data are the median and interquartile range. b The p values are from a Wilcoxon rank sum test. c The p values are from Fisher’s exact test or a Chi-Square test, as appropriate. d Data are the mean and standard deviation.