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. Author manuscript; available in PMC: 2023 Mar 10.
Published in final edited form as: J Immunol Regen Med. 2018 Apr 25;1:67–75. doi: 10.1016/j.regen.2018.03.002

Figure 4. Pancreatic tumorigenesis and progression is characterized by increased matricellular protein abundance.

Figure 4

(A) Heatmap of changes in the relative abundance of all matricellular proteins identified by data dependent global LC-MS/MS. (B) Variable of importance (VIP) plot (left) in which matricellular protein are ranked based on their contribution to the separation between groups in principal component analysis scores plot (right). A larger VIP score indicates that the variable is more important in defining the differences between all groups in PCA scores plot. (C) Correlation analysis of ECM components that correlate with Mannose receptor 1 (Mrc1) abundance based on relative abundance measures from data dependent global LC-MS/MS experiments.