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. 2023 Feb 21;28(5):2005. doi: 10.3390/molecules28052005

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© 2023 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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Anti-inflammatory effects of C. bovis on LPS-induced zebrafish inflammation model. (A) Toxicity of C. bovis treatment (n = 10). Larvae with cardiac edema, or body distortion, are defined as unhealthy. (B) The classification of inflammatory phenotypes in zebrafish embryos of different groups. The combined percentage of the medium and severe phenotypes was statistically analyzed among different groups (n > 10). Control: PBS injection; model: LPS injection. (C) The mRNA levels of IL-6, TNF-α, and CCL-2 in zebrafish embryos of different groups (n > 10). All the data are presented as the mean ± SEM of three independent experiments. # Compared with the control group; * compared with the model group; ## or **, p < 0.01.