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. 2023 Mar 2;12(5):1981. doi: 10.3390/jcm12051981

Table 2.

Most reported reasons for non-adherence (barriers to adherence). 1: also includes forgetfulness due to events that disrupt the routine of taking medicine as prescribed (i.e., being away for long time, having someone at home, being at restaurant, travelling). 2: problems in following the treatment plan, ignorance of life-long drug adherence, non-awareness of the chronic nature of diabetes, dislike of the taste of the medication, difficulty in swallowing due to the size of medication.

Reasons for Non-Adherence Number of Studies
Forgetfulness 1 28
Experiencing of side effects 15
High costs 12
Absence/disappearance of symptoms 9
Carelessness 8
Multiple medications 6
Procrastinating on refills or renewals of prescriptions 6
Feeling hassled or bored to take medication regularly 5
Worry about using medication regularly due to possible risk of unintended effects 5
Not accepting disease/feeling disease under control 4
Lack of confidence or poor communication with the physician/healthcare provider 4
Being too busy/time constraints 4
Social influence and environmental context 3
Complexity of treatment regimen 2
Inefficacy 2
Preference for herbal remedies 2
Others 2 5