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. 2023 Feb 28;12(5):1897. doi: 10.3390/jcm12051897

Table 3.

Symptomatic outcome following cholecystectomy in prospective studies.

Preoperative Proportion (%) Decline Incline Debuting
Pain attacks/biliary colic/biliary pain 42–100% ↓↓↓ (0%)
Unspecified/atypical pain 9–100% ↓↓ 0–7%
Dyspepsia 11–88% ↓↓ (↑↑↑) 0–6%
Heartburn 25–66% ↓↓ 1–8%
Regurgitation/reflux 11–72% ↓↓ (↑) 2–14%
Nausea 13–90% ↓↓↓ (↑↑↑) 0–2%
Vomiting 7–54% ↓↓↓ (↑↑↑) 0–1%
Fat or food intolerance 36–80% ↓↓↓ 2–13%
Indigestion/postprandial heaviness 14–78% ↓↓
Flatulence 15–88% 0–10%
Diarrhea 2–22% (→) ↑↑↑ 14–17%
Bloating/distension 37–82% ↓↓
Constipation 7–65%

Arrows indicate % change in proportion of patients reporting symptoms before versus after cholecystectomy as reported in most studies. ↓↓↓/↑↑↑ decline/incline of 60% or more; ↓↓/↑↑ decline/incline of 30–60% or more; ↓/↑ decline/incline of 30–60%; → % change less than 30%; – indicates no available studies or incomparable estimates between studies; () indicates estimates from single studies.