Table 1.
Demographic and clinical characteristics of women with RPL who had index pregnancies and who received dydrogesterone treatment vs. those who received no treatment.
| Dydrogesterone Treatment | No Dydrogesterone Treatment | p-Value | |
|---|---|---|---|
| n = 509 | n = 357 | ||
| Maternal age | |||
| Mean ± SD | 29.97 ± 5.894 | 29.86 ± 5.994 | 0.8 |
| Over 35 | 108 (21.2) | 67 (18.8) | 0.391 |
| Number of previous pregnancy losses (mean ± SD) * | 3.124 ± 1.620 | 3.197 ± 1.480 | 0.554 |
| Consanguineous marriages | 134 (26.3) | 76 (21.3) | 0.091 |
| BMI * | 0.154 | ||
| Lower than 20 | 55 (12.4) | 18 (8.2) | |
| 20–24.9 | 178 (40.2) | 81 (36.8) | |
| 25–29.9 | 108 (24.4) | 68 (38.6) | |
| Higher than 29.9 | 102 (23.0) | 53 (24.1) | |
| BMI ≥ 25 | 210 (47.4) | 121 (55.0) | 0.07 |
| Smoking * | 34 (6.8) | 16 (6.6) | 1 |
| Alcohol use * | 0 (-) | 0 (-) | - |
| Spontaneous pregnancy | 381 (87.8) | 285 (91.6) | 0.116 |
| Chronic diseases | |||
| APS | 94 (18.5) | 36 (10.1) | 0.001 |
| Hypothyroidism | 41 (8.1) | 42 (11.8) | 0.078 |
| Hypertension | 10 (2.0) | 5 (1.4) | 0.606 |
| Diabetes | 15 (2.9) | 15 (4.2) | 0.349 |
* Missing values: number of previous pregnancy losses: n = 118; BMI: n = 203; smoking: n = 121; alcohol use: n = 121; spontaneous pregnancy: n = 121.