Figure 8.
The protective effects of K. parviflora on neurogenesis in the co-culture between differentiated NE-4C and BV-2 cells treated with Aβ42. (A) IL-6 mRNA levels of BV-2 cells, (B) relative iNOS mRNA levels of BV-2 cells, (C) DCF fluorescence of BV-2 cells, (D) beta-III tubulin mRNA levels of differentiated NE-4C cells, and (E) MAP-2 mRNA levels of differentiated NE-4C cells. The values are mean ± SD of three independent experiments. The ### shows a significantly different between control and cells exposed to Aβ42 peptides without KP extract at p < 0.001 using one-way ANOVA followed by Tukey’s test. The * shows a significantly different between cells exposed to Aβ42 peptides without KP extract compared to cells exposed to Aβ42 peptides and various concentrations of KP extract (1–8 µg/mL) using one-way ANOVA followed by Tukey’s test. *, p < 0.05, **, p < 0.01, ***, p < 0.001.