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(a) Ce6-DNAzyme/[Cu(tz)] triggers both Type-I and Type-II PDT, as well as selective gene silencing by DNAzyme. (b) Illustration of heme negative feedback mechanism of CCPCA NPs. (c) CCPCA exhibited lower H2O2 content and RDPP expression (the study of intracellular O2), suggesting sufficient intracellular O2 generation ability (n.s. represents no signigicance). Reprinted with permission from Refs. (a) [94] 2021 John Wiley and Sons and (b,c) [96] 2022 Springer Nature.
