Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Results of the MST binding check assays.
| Compound | Ligand Concentration Displaying: | |
|---|---|---|
| Binding | No Binding | |
| 3a | 500 nM | 250 nM |
| 3b | 5 µM | 1 µM |
| 3c | 4 µM | 1 µM |
| 3d | 20 µM | 5 µM |
| 3ea | 500 nM | 250 nM |
| 3eb | 3.1 µM | 1.2 µM |
| 3f | 1 µM | 500 nM |
| 3g | 5 µM | 1 µM |
| 3h | 100 µM | 20 µM |
| 3d-pin | / | 100 µM |
| 3f-pin | 20 µM | 4 µM |
