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. 2023 Mar 6;15(5):1300. doi: 10.3390/nu15051300

Table 6.

Correlations between ophthalmological parameters and biomarkers of oxidative stress and inflammation in patients with keratoconus treated with DHA supplementation.

Ophthalmological Variables Oxidative Stress/
Inflammatory Biomarkers
Correlation Coefficient
(95% Confidence Interval)
K1, flat keratometry
  • -

    GSH/GSSG ratio

−0.51 (−0.79 to −0.006)
  • -

    IL-8

0.46 (−0.01 to 0.76)
K2, steep keratometry
  • -

    IL-4

0.65 (0.27 to 0.86)
  • -

    IL-10

0.53 (0.09 to 0.80)
Astigmatism axis
  • -

    TNF-α

−0.49 (−0.78 to −0.03)
Astigmatism degree
  • -

    GSH free

0.47 (0.0 to 0.77)
Central corneal thickness (CCT)
  • -

    IL-6

−0.46 (−0.76 to 0.0)
Chromatic aberration (CA)
  • -

    IL-10

0.55 (0.11 to 0.81)
Intraocular pressure (IOP)
(Goldmann applanation tonometry)
  • -

    GSH total

0.50 (00.5 to 0.78)
  • -

    GSH free

0.62 (0.21 to 0.84)
  • -

    GSH/GSSG

0.68 (0.31 to 0.87)
  • -

    IL-18

−0.59 (−0.83 to −0.17)

GSH: glutathione; GSSG: oxidized glutathione; IL: interleukin; TNF: tumor necrosis factor.