Table 2.
Physical characteristics of R-carvedilol-loaded transfersomes.
| Batch ID | Formulation ID |
Ratio | Characterization | |||||
|---|---|---|---|---|---|---|---|---|
| Drug | SPC | Tween 80 | Mean Particle Size (nm) ± SD | PDI ± SD | Zeta Potential (mV) ± SD | % Encapsulation Efficiency | ||
| 1-1 | T-RCAR 1 | 1 | 3 | 0 | 110.6 ± 0.57 | 0.18 ± 0.02 | 34.4 ± 0.60 | 71% |
| 1-2 | T-RCAR 1 | 1 | 3 | 0 | 91.88 ± 0.95 | 0.17 ± 0.02 | 38.83 ± 1.45 | 92% |
| 1-3 | T-RCAR 1 | 1 | 3 | 0 | 119.77 ± 1.75 | 0.13 ± 0.03 | 37.53 ± 1.23 | 71% |
| 107.42 ± 14.21 | 0.16 ± 0.026 | 36.92 ± 2.28 | 78 ± 12 | |||||
| 2-1 | T-RCAR 2 | 1 | 3 | 0.25 | 107.02 ± 1.36 | 0.16 ± 0.02 | 30.34 ± 0.74 | 83% |
| 2-2 | T-RCAR 2 | 1 | 3 | 0.25 | 91.46 ± 1.51 | 0.16 ± 0.05 | 32.87 ± 1.67 | 91% |
| 2-3 | T-RCAR 2 | 1 | 3 | 0.25 | 123.30 ± 4.94 | 0.12 ± 0.02 | 33.67 ± 1.89 | 81% |
| 107.26 ± 15.92 | 0.15 ± 0.023 | 32.29 ± 1.74 | 85 ± 5.5 | |||||
| 3-1 | T-RCAR 3 | 1 | 3 | 0.5 | 100.36 ± 0.39 | 0.17 ± 0.02 | 32.16 ± 2.06 | 81% |
| 3-2 | T-RCAR 3 | 1 | 3 | 0.5 | 89.22 ± 1.37 | 0.16 ± 0.02 | 34.6 ± 0.46 | 89% |
| 3-3 | T-RCAR 3 | 1 | 3 | 0.5 | 101.52 ± 3.85 | 0.14 ± 0.02 | 37.8 ± 0.15 | 81% |
| 97.03 ± 6.79 | 0.16 ± 0.015 | 34.85 ± 2.83 | 84 ± 4.6 | |||||