Table 7.

Changes in the serum levels of selected cytokines associated with cytokine storm at baseline and 10-week follow-up.

Variable	Group	Control	D3	p-Value
IL-1β (pg/mL)	Baseline	3.27 ± 1.37	3.22 ± 0.99	PB = 0.852
	Follow-up	3.59 ± 2.71	7.63 ± 2.36	PC < 0.001
	Change	0.32	4.41
	PA	0.574	<0.001
IL-6 (pg/mL)	Baseline	4.55 ± 2.62	5.5 ± 6.51	PB = 0.431
	Follow-up	4.85 ± 4.84	26.99 ± 14.47	PC < 0.001
	Change	0.30	21.49
	PA	0.750	<0.001
TNF-α (pg/mL)	Baseline	31.16 ± 5.22	33.34 ± 6.36	PB = 0.116
	Follow-up	33.65 ± 5.15	33.50 ± 6.18	PC = 0.910
	Change	2.49	0.16
	PA	0.100	0.899
IL-10 (pg/mL)	Baseline	2.20 ± 0.52	2.01 ± 0.59	PB = 0.159
	Follow-up	2.39 ± 1.39	4.46 ± 4.67	PC = 0.016
	Change	0.20	2.45
	PA	0.433	0.001

Abbreviations: P^A, p-value for paired sample t-test; P^B, p-value for two independent sample t-test at baseline; P^C, p-value for two independent sample t-test at follow-up of trial.