Table 2. Composition of Falciparome phage library.
Input sequences before collapsing on similarity | Identity threshold for collapsing byCD-HIT | # Final collapsed Protein sequences | |
---|---|---|---|
P. falciparum reference proteome | 3D7, IT (10,771 total) | 99% | 6372 |
P. falciparum variant sequences |
|
100% (90% for CSP) |
1205 |
Other variants |
P. reichnowi PfEMP1 (PFREICH) Anopheles - CE5 (5), SG6 (5) |
||
Anopheles salivary proteins | 53 proteins from 19 Anopheles species as described in Figure 1 of Arcà et al., 2017 | 98% | 708 |
Vaccine/Viral/Toxin sequences |
|
98% (90% for RotoAB) |
684 |
Laboratory positive controls |
|
98% | 11 |
TOTAL PROTEINS | 8,980 | ||
TOTAL PEPTIDES | 238,068 |