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. 2023 Feb 15;12:e81401. doi: 10.7554/eLife.81401

Table 2. Composition of Falciparome phage library.

Input sequences before collapsing on similarity Identity threshold for collapsing byCD-HIT # Final collapsed Protein sequences
P. falciparum reference proteome 3D7, IT (10,771 total) 99% 6372
P. falciparum variant sequences
  • PfEMP1 (431 from 3D7, IT, IGH, RAJ116, PFCLIN, IT4, DD2 genomes)

  • RIFIN (all 3D7+IT)

  • STEVOR (all 3D7+IT)

  • SURFIN (all 3D7+IT + 15)

  • AMA1 (2)

  • CSP (6)

  • MSPDBL1 (6)

  • MSPDBL2 (5)

  • PfMC2TM (all 3D7+IT)

100%
(90% for CSP)
1205
Other variants P. reichnowi PfEMP1 (PFREICH)
Anopheles - CE5 (5), SG6 (5)
Anopheles salivary proteins 53 proteins from 19 Anopheles species as described in Figure 1 of Arcà et al., 2017 98% 708
Vaccine/Viral/Toxin sequences
  • Tetanus

  • Diphtheria

  • Pertussis

  • EBV

  • Measles

  • Mumps

  • Rubella

  • Polio

  • RotoAB

98%
(90% for RotoAB)
684
Laboratory positive controls
  • GFAP

  • GFP

  • Gephryn

  • MYC, NR1

  • Tubulin (alpha/beta)

98% 11
TOTAL PROTEINS 8,980
TOTAL PEPTIDES 238,068