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. 2023 Mar 1;66(6):3664–3702. doi: 10.1021/acs.jmedchem.2c01229

Table 1. Chemical Structures, Enzyme Inhibition Profile, and Selectivity Index (SI) of Peptidomimetic Mpro Inhibitorsa.

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a

The main fragments explored as innovative P elements with respect to TG-0205221 (template molecule) are highlighted in red.