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. 2023 Mar 11;8:36. doi: 10.1038/s41541-023-00630-0

Fig. 3. COVID-19 risk by D57 antibody marker level in baseline SARS-CoV-2 negative vaccine recipients.

Fig. 3

Cumulative incidence of COVID-19 by Low, Medium, High tertile of D57 antibody marker level. a, c Anti-spike IgG concentration; b, c pseudovirus (PsV) neutralization ID50 titer. The overall P-value is from a generalized Wald-test p-value of the null hypothesis that the hazard rate is constant across the Low, Medium, and High tertile groups. The total number of cases across the Low, Medium, and High tertiles (N = 45) for each antibody marker differs from the numbers in Table 1 and Fig. 1 (N = 33, 22 for spike IgG, PsV-nAb ID50, respectively) because the 45 includes all vaccine breakthrough cases including those without D57 antibody marker data.