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. 2022 May 5;33(2):244–254. doi: 10.1038/s41370-022-00441-w

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Fig. 2 — a OH-MINCH (a DINCH metabolite) in US children. b 5cx-MEPTP (a DEHT metabolite) in US adults. Each symbol is a central value (i.e. median or geometric mean). The size of the symbols is related to the study-specific sample size (N) and its weight in the time-trend calculation (see Statistical methods, time-trend analysis). Data from the same data source (Study ID number: see Data traceability in the “PhthaLit” database) are identified by symbols with the same colour in all panels and figures. Grey area: 90% confidence interval.