Table 1.
AD | MCI | HC | ANOVA | |
---|---|---|---|---|
Cases | 14 | 12 | 16 | – |
Age | 73.7 ± 7.7a | 75.8 ± 7.6b | 63.1 ± 8.2 | 0.00012** |
Gender (Male/Female) | 8/6 | 6/6 | 7/9 | 0.74 |
IQ | 114 ± 16.9 | 118 ± 8.1 | 115 ± 9.4 | 0.68 |
NART | 12.2 ± 10.3 | 10.7 ± 7.1 | 12.6 ± 7.5 | 0.83 |
MMSE | 23.0 ± 3.6a | 28.0 ± 1.5 | 28.7 ± 1.7 | <0.0001** |
Rey Copy | 25.6 ± 10.8 | 32.2 ± 4.3 | 34.5 ± 2.8 | 0.022* |
Rey Imm | 5.2 ± 4.6a | 9.8 ± 6.3 | 18.2 ± 11.5 | 0.004* |
Rey Del | 3.2 ± 4.2a | 10.5 ± 6.6 | 18.0 ± 7.5 | <0.0001** |
WLM Imm | 15.4 ± 9.8a | 30.0 ± 10.5b | 45.2 ± 8.5 | <0.0001** |
WLM Del | 3.8 ± 6.3a | 13.1 ± 8.2b | 28.4 ± 6.2 | <0.0001** |
Hopkins Imm | 9.8 ± 8.8a | 18.3 ± 6.8b | 26.2 ± 8.6 | 0.00016** |
Hopkins Del | 1.6 ± 1.9a | 6.7 ± 9.1b | 12.4 ± 7.1 | 0.003* |
Hopkins RI | 5.0 ± 3.8a | 7.9 ± 3.9b | 11.4 ± 0.9 | <0.0001** |
LNS | 3.6 ± 2.4a | 6.3 ± 3.0a | 10.71 ± 3.20 | <0.0001** |
Semantic Fluency | 11.3 ± 3.2a | 14.7 ± 4.2b | 23.8 ± 8.6 | <0.0001** |
Verbal Fluency | 35.6 ± 11.9a | 38.7 ± 13.5b | 49.2 ± 12.9 | 0.038* |
HADS Anxiety | 6.8 ± 3.8 | 6.0 ± 3.9 | 5.2 ± 3.5 | 0.58 |
HADS Depression | 5.6 ± 4.3 | 4.0 ± 2.4 | 3.2 ± 3.6 | 0.28 |
SD standard deviation, NART National Adult Reading Test, MMSE Mini-Mental State Examination, Rey Rey–Osterrieth complex figure test, Imm immediate recall, Del delayed recall, WLM Wechsler Memory Scale–Logical Memory test, Hopkins Hopkins Verbal Learning Test, RI Recognition Index, LNS Letter-Number Sequencing, HADS Hospital Anxiety and Depression Scale.
*p < 0.05; **p < 0.001 in ANOVA.
aSignificant difference between Alzheimer’s dementia patients and healthy controls in post hoc comparisons (p < 0.05).
bSignificant difference between mild cognitive impairment patients and healthy controls in post hoc comparisons (p < 0.05).