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. 2022 Dec 12;13(3):1323–1335. doi: 10.21037/qims-21-1108

Table 4. The left ventricular systolic and diastolic function parameters in patients with TTS and normal controls at different times (t/P).

Parameters t1/P1 t2/P2 t3/P3 t4/P4 t5/P5 t6/P6
LVEDV (mL) 3.000/0.005 1.397/0.171 0.118/0.907 1.662/0.107 2.661/0.012 1.273/0.213
LVESV (mL) 14.092/<0.001 4.249/<0.001 1.208/0.235 8.953/<0.001 11.684/<0.001 2.795/0.009
LVSV (mL) 10.507/<0.001 2.295/0.028 1.429/0.162 7.023/<0.001 8.849/<0.001 1.129/0.268
LVEF (%) 28.458/<0.001 7.403/<0.001 2.012/0.052 18.653/<0.001 21.700/<0.001 3.868/0.001
E (m/s) 5.574/<0.001 6.807/<0.001 5.956/<0.001 1.97/0.058 0.844/0.405 1.028/0.312
A (m/s) 4.106/<0.001 3.384/0.002 3.335/0.003 0.594/0.557 0.942/0.353 0.297/0.768
E/A ratio 19.826/<0.001 23.444/<0.001 18.431/<0.001 3.585/0.001 0.400/0.692 2.543/0.016
E’ (cm/s) 5.949/<0.001 5.913/<0.001 4.680/<0.001 0.268/0.790 1.521/0.139 1.348/0.187
A’ (cm/s) 2.841/<0.001 2.749/<0.001 2.697/<0.001 0.230/0.820 0.389/0.700 0.160/0.874
E’/A’ ratio 23.311/<0.001 23.387/<0.001 19.73/<0.001 0.867/0.392 3.762/0.001 3.200/0.003
E/E’ ratio 3.483/0.001 0.695/0.490 0.035/0.972 2.174/0.038 2.849/0.008 0.549/0.586

The t1/P1, t2/P2, and t3/P3 were patients with TTS on admission and after 4 and 8 weeks vs. normal controls. The t4/P4 and t5/P5 were patients with TTS after 4 and 8 weeks vs. on admission. The t6/P6 was TTS patients after 8 weeks vs. after 4 weeks. LVESV, LVSV, and LVEF were measured by real-time 3-dimensional echocardiography. TTS, Takotsubo syndrome; LVEDV, left ventricular end-diastolic volume; LVESV, left ventricular end-systolic volume; LVSV, left ventricular stroke volume; LVEF, left ventricular ejection fraction; E, mitral inflow peak E-wave velocity; A, mitral inflow peak A-wave velocity; E’, mitral annular peak E’-wave velocity; A’, mitral annular peak A’-wave velocity.