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. 2023 Mar 10;9:90. doi: 10.1038/s41420-023-01382-5

Fig. 5. Htl signaling is required at early stages of embryogenesis to control the phagocytic ability of glia.

Fig. 5

Volume of apoptotic particles within CNS sections of (A) control embryos and embryos expressing htl RNAi or pyr RNAi with repoGal4 driver; B control embryos and embryos expressing htl RNAi or pyr RNAi or htl-CA alone or htl-CA with pyr RNAi with gcmGal4 driver. Graphs represent mean total volume of apoptotic particles within stacks of the CNS ± SEM, n = 5–9. Statistical significance was analyzed employing one-way ANOVA, ***p < 0.001, *p < 0.05, n.s. (not significant) p > 0.05. Note the non-significant increase in the volume of apoptotic cells in repoGal4-expressing embryos and the rescue of the pyr RNAi phagocytosis phenotype upon htl-CA expression at early stages (gcmGal4/UASpyrRNAi;UAShtl-CA).