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. 2022 Dec 26;128(6):1148–1154. doi: 10.1038/s41416-022-02105-w

Fig. 3. Predictive ability of TMB derived from RNA-seq.

Fig. 3

a TMB derived from RNA-seq is significantly different between responders and non-responders but is not predictive of overall patient survival time. b The threshold of RNA TMB is set to be equivalent to DNA TMB of 10 mutations/MB and 15 of 63 samples are TMB high. c AUC with confidence intervals derived from a bootstrap analysis of the patient response.